Tobias Mühlethaler

This study identifies molecular determinants of high-affinity PDZK1 binding to URAT1 using biophysical and structural methods, revealing species-specific interactions.

This study identifies xenorceptides, a new class of antibiotics that target BamA in Gram-negative bacteria, showing potent activity and limited resistance.

The paper captures the release of a photopharmacological drug from tubulin using time-resolved serial crystallography and shows how ligand release triggers conformational changes.