Author

Julie Andries

Ghent UniversityORCID 0000-0001-8446-9786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Danielle M. ClancyiD· 1 shared Jan FélixiD· 1 shared Martin TouliD· 1 shared Savvas N. SavvidesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

Danielle M. ClancyORCID

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1 paper

Recent·Most cited

Structural basis of pro-inflammatory signaling via the Interleukin-36 receptor (IL-36R) mediated by IL-36γ and IL-37

Julie Andries, Martin Toul, Jan Félix, Danielle M. Clancy, Savvas N. Savvides

This study reveals the structural mechanisms of IL-36R activation by IL-36γ and IL-37 and spesolimab's allosteric antagonism, providing a blueprint for therapeutic targeting.

bioRxiv · Feb 22, 2025 · PreprintImmunology