Author

Sarah Krantz

National Institutes of HealthORCID 0000-0001-8451-2238Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Brad BelliD· 1 shared Brad St. CroixiD· 1 shared Francesco RaimondiiD· 1 shared Katherine LundiD· 1 shared Kavita Yang SariniD· 1 shared Natalia De Oliveira RosaiD· 1 shared Natalia Salinas ParraiD· 1 shared Ramiro Iglesias‐BartoloméiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Brad BellORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedDec 29, 2025

Dissection of Gαs and Hedgehog signaling crosstalk reveals therapeutic opportunities to target adenosine receptor 2b in Hedgehog-dependent tumors

Sarah Krantz, Brad Bell, Katherine Lund…·Ramiro Iglesias‐Bartolomé

The paper identifies Gs pathway inactivation as an SMO-independent Hedgehog signaling driver in BCC and shows adenosine 2B receptor activation can counteract SMO-driven oncogenesis.

1 citation

mousebulk RNA-seq

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