ImmunologybioRxivPreprint
Scalable expansion of human iNKT cells: single-cell profiling and in vivo control of GvHD with preserved GvL activity
Jordan Brouard, Cristina Caraiman, Ghislain Fiévet…·Marie‐Thérèse Rubio
This paper develops a scalable method to expand human CD4- iNKT cells from PBMCs using IL-15 and -GalCer, showing improved GVHD control and GVL activity in preclinical models.
DOI 10.64898/2026.09.11.750594