Marie‐Thérèse Rubio

This paper develops a scalable method to expand human CD4- iNKT cells from PBMCs using IL-15 and -GalCer, showing improved GVHD control and GVL activity in preclinical models.

This study shows that IL-12 enhances the anti-glioblastoma efficacy of GD2-targeted CAR-T and CAR-iNKT cells by improving their persistence and function after repeated antigen exposure.

This study profiles genomic and immunogenomic features of eAML, finding clonal branching and immune editing, with FLT3 mutations in relapsed cases.