Jordan Brouard

The paper identifies TEM1657, a small molecule that modulates mitochondria and suppresses NFKBIZ pathway to resolve Th17-driven psoriatic inflammation.

This paper develops a scalable method to expand human CD4- iNKT cells from PBMCs using IL-15 and -GalCer, showing improved GVHD control and GVL activity in preclinical models.

This study shows that IL-12 enhances the anti-glioblastoma efficacy of GD2-targeted CAR-T and CAR-iNKT cells by improving their persistence and function after repeated antigen exposure.

The paper identifies immune endotypes in OA synovial tissue using integrated molecular and spatial profiling to guide precision medicine.