Russell A. Norris

This study identifies two genome-wide significant loci associated with hypermobile Ehlers-Danlos syndrome, implicating neuroimmune and pain signaling pathways and highlighting genetic correlations with multiple comorbid conditions.

This study develops hypoimmunogenic hPSC-derived cardiac organoids that evade immune rejection and repair damaged hearts in animal models.

The paper performs a genome-wide association meta-analysis of mitral valve prolapse, identifying new risk loci and genes involved in cardiac development and aging.

The paper characterizes open chromatin profiles in human mitral valves to identify functional variants and target genes at MVP risk loci.

This paper develops a human pluripotent stem cell model to study valvulogenesis and disease, showing it can recapitulate valve development and disease traits like mitral valve prolapse.