Developmental BiologyNaturePeer-reviewed
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Hair-bearing human skin generated entirely from pluripotent stem cells
Jiyoon Lee, Cyrus C. Rabbani, Hongyu Gao…·Karl R. Koehler
Stepwise modulation of TGFβ, BMP, and FGF signaling in human pluripotent stem cell aggregates generates innervated, pigmented hair-bearing skin organoids that form planar human skin when grafted onto nude mice.