Author

Jiyoon Lee

Boston Children's HospitalORCID 0000-0002-5561-5331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Karl R. KoehleriD· 3 shared Jin KimiD· 2 shared Sara A. SerdyiD· 2 shared Alexander KimiD· 1 shared Andrew J. FilbyiD· 1 shared Anh Phuong LeiD· 1 shared Anna Dubois· 1 shared Antony RoseiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersDevelopmental Biology

Karl R. KoehlerORCID

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3 papers

Recent·Most cited

Lateral plate mesoderm directs human amnion and ventral skin organoid formation

Anh Phuong Le, Jin Kim, Qianyi Ma, Kelly Y Gim, Sara A. Serdy, Edward H Lee, Shariqa T Shaila, Taiki Nakajima, Carl A. Nist-Lund, Ian A. Glass, Yosuke Mai, Laura C. Nuzzi, Catherine T. McNamara, Brian I. Labow, Liang Sun, , Karl R. Koehler

This study generates human ventral skin and amnion-like organoids by adjusting signaling and cellular composition, revealing key developmental pathways and interactions.

bioRxiv · Nov 5, 2025 · PreprintDevelopmental Biology

A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis

Nusayhah Hudaa Gopee, Ni Huang, Bayanne Olabi, Chloe Admane, Rachel Anne Botting, April Rose Foster, Fereshteh Torabi, Elena Winheim, Dinithi Sumanaweera, Issac Goh, Mohi Miah, Emily Stephenson, Win Min Tun, Pejvak Moghimi, Benjamin M. Rumney, , Muzlifah A. Haniffa

This study creates a prenatal human skin cell atlas, revealing immune cells' role in skin development and showing their impact on vascular and hair follicle formation.

bioRxiv · Oct 12, 2023 · PreprintDevelopmental Biology

Hair-bearing human skin generated entirely from pluripotent stem cells

Jiyoon Lee, Cyrus C. Rabbani, Hongyu Gao, Matthew R. Steinhart, Benjamin M. Woodruff, Zachary E. Pflum, Alexander Kim, Stefan Heller, Yunlong Liu, Taha Z. Shipchandler, Karl R. Koehler

Stepwise modulation of TGFβ, BMP, and FGF signaling in human pluripotent stem cell aggregates generates innervated, pigmented hair-bearing skin organoids that form planar human skin when grafted onto nude mice.

Nature · Jun 3, 2020Peer-reviewedDevelopmental Biology✦ In-depth digest