Author

Claude Prigent

Centre National de la Recherche ScientifiqueORCID 0000-0001-8515-8699Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnès MéreauiD· 1 shared Amit K. BeheraiD· 1 shared Arun Prasath DamodaraniD· 1 shared Aurore M. M. Dupuy· 1 shared Bandana KumariiD· 1 shared Camille E. Tessier· 1 shared Camille El Harrif· 1 shared Elise Douillard· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Agnès MéreauORCID

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2 papers

Recent·Most cited

Cancer BiologyEMBO Molecular MedicinePeer-reviewedAug 26, 2025

Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy

Camille E. Tessier, Jennifer Derrien, Aurore M. M. Dupuy…·Vincent J. Guen

This study shows primary cilia in TNBC cells contribute to chemoresistance by supporting EMT-driven heterogeneity and stemness, and inhibiting ciliogenesis reduces this resistance.

10 citationstop 4%

humanorganoid / primary culture

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Molecular BiologyJournal of Biological ChemistryPeer-reviewedNov 17, 2024

Aurora-A phosphorylates splicing factors and regulates alternative splicing

Arun Prasath Damodaran, Olivia Gavard, Jean‐Philippe Gagné…·Claude Prigent

This study identifies Aurora-A as a splicing kinase that regulates alternative splicing by phosphorylating splicing factors and altering RNA motifs in affected regions.

14 citations

humanbulk RNA-seq

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