Molecular BiologybioRxivPreprint
Highly resolved tumor architecture via matched spatial and nucleus transcriptomics from a single tissue section
Marcos Machado, Mengxiao He, Leire Alonso Galicia…·Reza Mirzazadeh
SIMPlex generates matched spatial and single-nucleus transcriptomic profiles from the same tissue section to resolve cell states with spatial signatures in mouse and human cancer tissues.