Gabriela Andrea Hernandez Gonzalez

The paper identifies two perispeckle networks that partition interchromatin space, showing differential gene expression associations compared to nuclear speckles.

The paper shows HSPA1 genes move directionally near nuclear speckles, dependent on HSF1 and DDX39B condensates, enhancing gene expression.

The paper identifies dynamic multiphase connections between nuclear speckles that enable coordinated protein trafficking in response to physiological demands.

The paper examines genome organization in human cells relative to nuclear locales, finding that gene expression and replication timing correlate with different nuclear structures and that LADs and iLADs compete for lamina attachment.