Pankaj Chaturvedi

The paper identifies acidic transcription factors that position genomic regions near nuclear speckles through both transcription-dependent and independent mechanisms.

The paper identifies two perispeckle networks that partition interchromatin space, showing differential gene expression associations compared to nuclear speckles.

The paper shows that MALAT1 long noncoding RNA forms condensates with splicing factors to regulate hypoxia-induced alternative splicing near nuclear speckles.

The paper shows HSPA1 genes move directionally near nuclear speckles, dependent on HSF1 and DDX39B condensates, enhancing gene expression.