Author

Marta Cecylia Tapia

University of CopenhagenORCID 0000-0001-8529-2740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Nicholas T. CrumpiD· 2 shared Ross ThorneiD· 2 shared Thomas A. MilneiD· 2 shared Anindita RoyiD· 1 shared B. Christoffer LagerholmiD· 1 shared Edward R. MorrisseyiD· 1 shared Emmanouela RepapiiD· 1 shared Erica Ballabio· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Nicholas T. CrumpORCID

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2 papers

Recent·Most cited

GenomicsGenome ResearchPeer-reviewedJul 1, 2021

Phenotypic analysis of an MLL-AF4 gene regulatory network reveals indirect CASP9 repression as a mode of inducing apoptosis resistance.

Joe R. Harman, Ross Thorne, Max Jamilly…·Thomas A. Milne

The paper constructs a gene regulatory network for MLL-AF4 to reveal an indirect repression of CASP9 via RUNX1 as a mechanism of apoptosis resistance.

31 citations

humanChIP-seq

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Molecular BiologyNature CommunicationsPeer-reviewedJan 11, 2021

BET inhibition disrupts transcription but retains enhancer-promoter contact

Nicholas T. Crump, Erica Ballabio, Laura Godfrey…·Thomas A. Milne

The paper shows BET inhibition reduces transcription but not enhancer-promoter contacts, suggesting these processes are separable.

123 citationstop 1%

experimental assay

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