Author

Tsz Long Chu

Karolinska InstitutetORCID 0000-0001-8553-6880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Anna Xiaodan YuiD· 1 shared Kathryn S.E. CheahiD· 1 shared Kwok Yeung TsangiD· 1 shared Mingpeng KongiD· 1 shared Peikai CheniD· 1 shared Zhijia TaniD· 1 shared Zhongjun ZhouiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Anna Xiaodan YuORCID

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1 paper

Recent·Most cited

MMP14 cleaves PTH1R in the chondrocyte derived osteoblast lineage, curbing signaling intensity for proper bone anabolism

Tsz Long Chu, Peikai Chen, Anna Xiaodan Yu, Mingpeng Kong, Zhijia Tan, Kwok Yeung Tsang, Zhongjun Zhou, Kathryn S.E. Cheah

The paper identifies MMP14 as a regulator of PTH signaling in osteoblast lineage cells, showing that MMP14 cleavage of PTH1R reduces signaling intensity, promoting bone anabolism.

eLife · Mar 9, 2023Peer-reviewedDevelopmental Biology