Pablo Rivera‐Fuentes

This paper uses single-molecule fluorescence blinking to identify proteins and their modifications by analyzing the physicochemical environment of their surface.

This study shows S. aureus persists in musculoskeletal tissues despite antibiotic therapy, with residual bacteria capable of causing relapse.

BioPipelines provides an open-source Python framework for computational protein and ligand design, enabling multi-step workflows with minimal code and integration of over 30 tools.

The paper develops a ratiometric fluorescent pH sensor for Gram-positive and Gram-negative bacteria, validated in E. coli, S. epidermidis, and MRSA, enabling real-time pH tracking and identification of pH-sensitive phenotypes.

The paper maps Staphylococcus aureus microgeography in human tissue using AI-guided imaging and finds antibiotic failure is linked to intracellular bacterial persistence and metabolic constraints.

The paper measures redox potentials in membraneless organelles and finds nuclear EGSH is stable and matches cytosolic levels, while MLOs reflect their environment.

The paper characterizes the redox state of glutathione in the Golgi apparatus, finding it to be highly oxidizing with low GSH concentration.

The paper develops multivalent peptide probes to study the chromocenter microenvironment in living cells, revealing that heterochromatin compartments are less dense and more dynamic than in vitro HP1 condensates.