Emily L. Starke

This study shows dFMRP recruits miRISC to repress translation of target mRNAs in Drosophila, independent of deadenylation and requiring AGO1 and GW182.

This study shows that mutations in the KH domains of FMRP impair RNA granule formation and function in Drosophila, linking these defects to FXS pathogenesis.

This study creates a Drosophila model of Vps54 loss-of-function and shows it leads to shortened lifespan, muscle atrophy, and locomotor defects similar to the wobbler mouse.

This study shows that Vps54 regulates Drosophila neuromuscular junction development and postsynaptic density composition through Rab7-dependent endosomal trafficking.