Molecular BiologyStructurePeer-reviewed
The effect of G-quadruplexes on TDP43 condensation, distribution, and toxicity
Emily G. Oldani, Kevin M Reynolds Caicedo, McKenna E. Spaeth Herda…·Scott A. Horowitz
This study shows that RNA G-quadruplexes influence TDP43 condensation and toxicity in different cell types, suggesting targeting these structures could be a new approach for treating protein misfolding diseases.