MicrobiologyPLoS PathogensPeer-reviewed
Hydrogen sulfide (H2S) coordinates redox balance, carbon metabolism, and mitochondrial bioenergetics to suppress SARS-CoV-2 infection.
9 citations
Author
Nitish Malhotra
Tata Institute of Fundamental ResearchORCID 0000-0001-8580-9623Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2025 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 37 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 shared papersMicrobiology
Aswin Sai Narain SeshasayeeORCID
Mutual co-authors in cluster
4 papers
Recent·Most cited
- MicrobiologybioRxivPreprint
Bioenergetic reprogramming of macrophages reduces drug tolerance in Mycobacterium tuberculosis
Vikas Yadav, Sarthak Sahoo, Nitish Malhotra…·Amit Singh
This study shows that altering macrophage metabolism can reduce drug tolerance in Mycobacterium tuberculosis by affecting bacterial redox states.
DOI 10.1101/2025.01.24.634842 - GenomicsGenome Biology and EvolutionPeer-reviewed
Replication-dependent organisation constrains positioning of long DNA repeats in bacterial genomes
Nitish Malhotra, Aswin Sai Narain Seshasayee
The paper identifies long DNA repeats in bacterial genomes and shows their positioning is non-random and constrained by replication-dependent organisation in fast and slow-growing bacteria.
- GenomicsmSpherePeer-reviewed
Laboratory Evolution Experiments Help Identify a Predominant Region of ΔrnhA-dnaA Constitutive Stable DNA Replication Initiation
Reshma T Veetil, Nitish Malhotra, Akshara Dubey, Aswin Sai Narain Seshasayee
The paper uses laboratory evolution experiments to show that E. coli initiates constitutive stable DNA replication (cSDR) predominantly in a region ~0.6 Mb clockwise of oriC, and that genome inversions help resolve replication-transcription conflicts.
11 citations