José Rodrı́guez-Álvarez

The paper investigates how SSAO/VAP-1 affects BBB dysfunction and vascular BDNF release, leading to reduced synaptic markers in neurons in an Alzheimer's context.

This study investigates how β-amyloid and tau pathologies affect different neural circuits in a novel Alzheimer's disease mouse model, revealing region-specific synaptic, behavioral, and molecular changes.

The paper identifies CREB/CRTC1-regulated gene programs that link synaptic activity to transcriptional control of NMDA receptor-mediated plasticity and memory in hippocampal neurons.

This study shows that Nr4a2 activation prevents oAβ-induced synaptic dysfunction and memory deficits in AD mouse models.

This study shows that beta-hydroxybutyrate (BHB) improves AMPA receptor levels and cognitive performance in mice exposed to a high-fat diet.

This study investigates how presenilin dysfunction affects tau pathology through autophagy and proteasome pathways in familial Alzheimer's disease.