Author

Derya R. Shimshek

Novartis (Switzerland)ORCID 0000-0001-8602-7850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Anna NeuhausiD· 1 shared Annick WaldtiD· 1 shared Carole Manneville· 1 shared Caroline Gubser KelleriD· 1 shared Christian Lambert· 1 shared Claudia Patiño· 1 shared Daniel J. GreenwoodiD· 1 shared Daniela C. IvaniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Anna NeuhausORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 19, 2026

GPNMB enables lysosomal adaptation required for myelin clearance and nerve regeneration after peripheral nerve injury

Najwa Ouali Alami, Moh Panesar, Michael Obrecht…·Michael Bidinosti

This study identifies GPNMB as a critical regulator of lysosomal function in macrophages, essential for myelin clearance and nerve regeneration after peripheral nerve injury.

DOI 10.64898/2026.10.12.758439

mouseexperimental assay

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NeuroscienceCell ReportsPeer-reviewedMay 1, 2022

Sustained TREM2 stabilization accelerates microglia heterogeneity and Abeta pathology in a mouse model of Alzheimer s disease

Rahul Dhandapani, Marilisa Neri, Mario Bernhard…·Ivan Galimberti

This study shows that reduced TREM2 proteolytic cleavage in mice increases microglial heterogeneity and accelerates Abeta pathology in Alzheimer's disease.

60 citationstop 4%

mousebulk RNA-seq

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