Author

Rahul Dhandapani

European Molecular Biology Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Emerald Perlas· 2 shared Linda NocchiiD· 2 shared Mariano MaffeiiD· 2 shared Paul A. HeppenstalliD· 2 shared Ahmad Fawzi HussainiD· 1 shared Andrei TraistaiD· 1 shared Anna NeuhausiD· 1 shared Annick WaldtiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersNeuroscience

Emerald Perlas

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3 papers

Recent·Most cited

Sustained TREM2 stabilization accelerates microglia heterogeneity and Abeta pathology in a mouse model of Alzheimer s disease

Rahul Dhandapani, Marilisa Neri, Mario Bernhard, Irena Brzak, Tatjana Schweizer, Stefan Rudin, Stefanie Joller, Ramon Berth, Jasmin Kernen, Anna Neuhaus, Annick Waldt, Rachel Cuttat, Ulrike Naumann, Caroline Gubser Keller, Guglielmo Roma, , Ivan Galimberti

This study shows that reduced TREM2 proteolytic cleavage in mice increases microglial heterogeneity and accelerates Abeta pathology in Alzheimer's disease.

Cell Reports · May 1, 2022Peer-reviewedNeuroscience

Control of mechanical pain hypersensitivity through ligand-targeted photoablation of TrkB positive sensory neurons

Rahul Dhandapani, Cynthia Mary Arokiaraj, Francisco José Taberner, Paola Pacifico, Sruthi Raja, Linda Nocchi, Carla Portulano, Federica Franciosa, Mariano Maffei, Ahmad Fawzi Hussain, Fernanda de Castro Reis, Luc Reymond, Emerald Perlas, Simone Garcovich, Stefan Barth, , Paul A. Heppenstall

This study identifies TrkB-expressing sensory neurons as key to mechanical allodynia and demonstrates their ablation as a treatment for neuropathic pain.

Nature Communications · Apr 18, 2018Peer-reviewedNeuroscience

Molecule guided laser ablation as a novel therapeutic strategy to control itch.

Linda Nocchi, Mariangela D’Attilia, Nainika Roy, Rahul Dhandapani, Andrei Traista, Mariano Maffei, Laura Castaldi, Emerald Perlas, Paul A. Heppenstall

This paper develops a molecule-guided laser ablation strategy to control itch by targeting itch-sensing neurons in mouse models of skin diseases.

bioRxiv · Nov 27, 2017 · PreprintNeuroscience