Author

Holly L. Roach

Centre for Human GeneticsORCID 0000-0001-8610-1723Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Guifeng WeiiD· 1 shared Heather A. CokeriD· 1 shared Lisa RodermundiD· 1 shared Mafalda R. AlmeidaiD· 1 shared Neil BrockdorffiD· 1 shared Tatyana B. NesterovaiD· 1 shared

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2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Guifeng WeiORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJan 9, 2025

N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics

Guifeng Wei, Heather A. Coker, Lisa Rodermund…·Neil Brockdorff

This study shows that m6A modification on Xist RNA promotes its turnover, which regulates XCI dynamics, and that the NEXT complex mediates this turnover independently of YTHDC1.

4 citations

mousebulk RNA-seq

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