Xavier Hernandez‐Alias

The paper introduces UbSeRP to map co-translational ubiquitination across the translatome, revealing RQC substrates, biophysical features predicting RQC, and aging-related changes in CTU.

The paper investigates how arboviruses like chikungunya virus maintain persistent infections in mosquito cells through translational repression of viral RNA without affecting host cell fitness.

This paper introduces nucleotide dependency analysis to identify genomic functional elements, showing it outperforms existing methods in detecting regulatory elements and RNA structures.

The paper uses protein-to-mRNA ratios from human tissues to develop a codon optimizer algorithm that improves tissue-specific protein expression.

This study shows that human viruses adapt their codon usage to match the translational machinery of the tissues they infect, with SARS-CoV-2 showing improved adaptation to upper respiratory airways.

The paper examines translational efficiency across healthy and tumor tissues, finding it correlates with proliferation and specific codon usage patterns.