Maximilian Seidel

The paper introduces UbSeRP to map co-translational ubiquitination across the translatome, revealing RQC substrates, biophysical features predicting RQC, and aging-related changes in CTU.

The paper identifies importins that bind nascent proteins co-translationally in yeast, showing their role in preventing aggregation and integrating with ribosome-associated chaperones.

The paper identifies co-translational assembly domains in proteins that facilitate interactions between nascent chains and fully synthesized subunits, revealing their role in regulating complex assembly pathways.