Author

Valentina Poli

Boston Children's HospitalORCID 0000-0001-8637-8204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Ivan ZanoniiD· 2 shared Alex G Cuenca· 1 shared Andrew CromptoniD· 1 shared Anne Chu· 1 shared Benjamin A. GarciaiD· 1 shared Benson M. GeorgeiD· 1 shared Carolina Bras Costa· 1 shared Federica Meloni· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Ivan ZanoniORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 5, 2025

DNASE1L3 surveils mitochondrial DNA on the surface of distinct mammalian cells

Jennifer Porat, Valentina Poli, Karim Almahayni…·Ryan A. Flynn

This study shows DNASE1L3 clears surface DNA on B and T cells, and variants in DNASE1L3 are linked to higher surface DNA levels in autoimmune disease.

1 citation

humanmouse

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 21, 2023

Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.

Marco Di Gioia, Valentina Poli, Piao J Tan…·Ivan Zanoni

The paper shows host-derived oxidized phospholipids initiate effector-triggered immunity, leading to lethality upon microbial encounter, and demonstrates that blocking oxPLs reduces inflammation and host death.

DOI 10.1101/2023.11.21.568047

mousehuman

𝕏 PostBluesky