Karim Almahayni

This study shows DNASE1L3 clears surface DNA on B and T cells, and variants in DNASE1L3 are linked to higher surface DNA levels in autoimmune disease.

The paper investigates glycocalyx dynamics using interferometric scattering microscopy and finds a strong correlation between glycan structure and system dynamics.

This study visualizes individual sugars within glycans on the cell surface using angstrom-resolution fluorescence microscopy combined with metabolic labeling.

This study introduces Glycan Atlassing, a method using DNA-tagged lectin labeling and metabolic oligosaccharide engineering to map glycocalyx architecture at nanometer resolution, revealing spatial relationships that reflect cellular state.