Author

Om Prakash Dwivedi

University of HelsinkiORCID 0000-0001-8670-7717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Isabella ArtneriD· 2 shared Leif GroopiD· 2 shared Rashmi B. PrasadiD· 2 shared Timo OtonkoskiiD· 2 shared Vikash ChandraiD· 2 shared Andria Theodoulou· 1 shared Ann-Marie T. Richard· 1 shared Anna L. GloyniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Isabella ArtnerORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedOct 26, 2022

The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α

Vikash Chandra, Hazem Ibrahim, Clémentine Halliez…·Timo Otonkoski

This study shows that TYK2 is critical for β-cell development by regulating KRAS and IFN responses, suggesting TYK2 inhibition as a therapeutic target for type 1 diabetes.

55 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsNature GeneticsPeer-reviewedNov 1, 2019

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Om Prakash Dwivedi, Mikko Lehtovirta, Benoît Hastoy…·Leif Groop

The paper shows that a loss-of-function variant in ZnT8 improves insulin secretion and protects against type 2 diabetes by enhancing glucose responsiveness and proinsulin conversion.

144 citationstop 1%

humanexperimental assay

𝕏 PostBluesky