Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens
Temitayo Olagunju, Mariia Pospelova, John C. Schwartz, Michelle R. Mousel, Lindsay M. W. Piel, Paige C. Grossman, Kathryn P. Huyvaert, Kristen L. Kuhn, Tajbir Raihan, Morgan R Stegemiller, Sarem F. Khilji, Gordon K. Murdoch, Ahmed Tibary, Lisette P. Waits, Arang Rhie, , Brenda M. Murdoch
This paper presents a telomere-to-telomere genome assembly of bighorn sheep, revealing immune gene differences that may explain their susceptibility to respiratory pathogens.
bioRxiv · Sep 30, 2025 · PreprintGenomics