Author

Joseph R Rouse

Emory UniversityORCID 0000-0001-8675-904XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alyssa M. McLeland· 1 shared Andrew L. RouthiD· 1 shared Angelica L. Morgan· 1 shared Bryan A. JohnsoniD· 1 shared David Hughes WalkeriD· 1 shared Jordan T. Murray· 1 shared Kumari G. Lokugamage· 1 shared Leah K. Estes· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alyssa M. McLeland

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1 paper

Recent·Most cited

SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness.

Yiyang Zhou, Yani P. Ahearn, Kumari G. Lokugamage, Angelica L. Morgan, R. Elias Alvarado, Leah K. Estes, William M. Meyers, Alyssa M. McLeland, Jordan T. Murray, Joseph R Rouse, Meenakshi Kar, Mehul S. Suthar, David Hughes Walker, Bryan A. Johnson, Andrew L. Routh, Vineet D. Menachery

This study shows SARS-CoV-2 NSP15 (EndoU) regulates RNA recombination and viral fitness, with its loss reducing replication but increasing inflammation and defective genomes.

Nature Communications · Dec 2, 2025Peer-reviewedMicrobiology