Simon Rayner

This study shows that the TNKS inhibitor OM-153 reduces fibrosis markers and ECM expression in multiple preclinical IPF models by inhibiting WNT/β-catenin and YAP signaling.

This study examines the link between close-range proximity and oral microbiota similarity in children, finding that more time spent in proximity correlates with greater microbiota similarity.

This study shows that cell-cell fusion in NSCLC leads to increased chemoresistance and tumor aggressiveness by creating hybrid cells with enhanced fitness and genomic heterogeneity.

The paper evaluates two additional miRNA library preparation kits, confirming that miRNA abundance biases are kit-specific and affect dataset comparability.

This study evaluates six commercial low-input miRNA library prep kits, finding differences in detection sensitivity and differential expression but no kit fully captures all expected miRNAs.

The paper introduces a deep learning method for miRNA target prediction that analyzes the entire miRNA and 3UTR mRNA, outperforming existing methods by considering non-seed region interactions.