Author

Nathaniel T. Kenton

ORCID 0000-0001-8730-5728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Organism:virus· 1

Frequent Co-Authors

Alpha A. LeeiD· 2 shared Annette von DelftiD· 2 shared D. FearoniD· 2 shared F. von DelftiD· 2 shared Haim Michael BarriD· 2 shared Noa Lahav· 2 shared Peter George MarplesiD· 2 shared Xiaomin NiiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBiochemistry

Alpha A. LeeORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 8, 2025

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors

Xiaomin Ni, R. Blake Richardson, Andre Schutzer Godoy…·F. von Delft

The paper identifies fragment binders and mutationally intolerant sites in Zika virus NS2B-NS3 protease to develop resistance-resilient antiviral inhibitors.

18 citationstop 3%

virusexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintJun 19, 2025

Discovery of orally bioavailable Zika virus NS2B-NS3 protease inhibitors with efficacy in a murine infection model

Nathaniel T. Kenton, Haim Michael Barr, Artem Cherepakha…·Alpha A. Lee

The paper identifies orally bioavailable inhibitors of the Zika virus NS2B-NS3 protease that show antiviral activity in vitro and reduce viral RNA load in a murine infection model.

3 citations

mouseexperimental assay

𝕏 PostBluesky