Carmen Pin

The paper examines how intestinal stem and progenitor cells respond to inflammation in IBD, finding distinct transcriptional changes and new immune-responsive cell states.

This paper presents a multi-scale agent-based model of intestinal crypt dynamics, showing how signaling pathways and feedback loops govern homeostasis, injury, and recovery.

This study shows zebrafish enteric glia can proliferate and generate enteric neurons, similar to brain neural stem cells, and are regulated by Notch signaling.

This study investigates how acute and chronic inflammatory cell death affects epithelial cell migration in the intestinal villi using computational models and cell-tracking methods.

The paper develops a hierarchical Bayesian framework to model spatiotemporal dynamics of intestinal epithelium proliferation and migration under different conditions, concluding a proliferation-driven model is sufficient for most time-scales.