Pascal Hols A

The paper identifies a conserved transporter-repressor module in streptococci that directly couples bacteriocin detection to transcriptional activation, revealing a minimalist and rapid mechanism for antimicrobial peptide resistance.

The paper shows that S. salivarius uses both peptides and organic molecules to activate its quorum sensor, revealing a new signaling mechanism in bacterial communication.

This paper identifies novel class II bacteriocins in Streptococcus salivarius using bioinformatics and synthetic biology, revealing 50 candidates active against Gram-positive pathogens.