Author

Adrien Knoops

Concordia UniversityORCID 0000-0002-6250-906XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:yeast· 3 Research Focus:cell type annotation· 2 Assay:CRISPR screen· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Mackenzie ThornburyiD· 3 shared Vincent J. J. MartiniD· 3 shared Malcolm S. WhitewayiD· 2 shared David H. KwaniD· 1 shared Félix JaumauxiD· 1 shared Gabriel E. Remondetto· 1 shared Iain Summerby-Murray· 1 shared Jacques MahilloniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersSynthetic Biology

Mackenzie ThornburyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Biosensor-guided genome-wide CRISPR screens enable cis,cis-muconic acid overproduction in yeast

Mohamed A. Nasr, Adrien Knoops, Mackenzie Thornbury, Meghan Davies, David H. Kwan, Vincent J.J. Martin

This study uses biosensor-guided CRISPR screens in yeast to identify genetic targets that enhance production of cis,cis-muconic acid and protocatechuic acid.

bioRxiv · Nov 3, 2026 · PreprintSynthetic Biology

Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus

Mackenzie Thornbury, Raha Parvizi Omran, Lalit Kumar, Adrien Knoops, Raghad Abushahin, Malcolm S. Whiteway, Vincent J. J. Martin

The paper uses a trifunctional CRISPR screen to identify gene perturbations that enhance fumaric acid tolerance and production in Kluyveromyces marxianus.

ACS Synthetic Biology · Nov 24, 2025Peer-reviewedSynthetic Biology

Sequencing of a dairy isolate unlocks Kluyveromyces marxianus as a host for lactose valorization

Mackenzie Thornbury, Adrien Knoops, Iain Summerby-Murray, James S. Dhaliwal, Sydney Johnson, Joseph Christian Utomo, Jaya Joshi, Lauren Narcross, Gabriel E. Remondetto, Michel Pouliot, Malcolm S. Whiteway, Vincent J. J. Martin

This study sequences and annotates the genome of Kluyveromyces marxianus Y-1190, identifies genetic factors for lactose metabolism, and develops tools for genetic manipulation to enhance its use in industrial biotechnology.

ACS Synthetic Biology · Jul 8, 2025Peer-reviewedSynthetic Biology

Uncovering the class II-bacteriocin predatiome in salivarius streptococci

Julien Damoczi, Adrien Knoops, Marie-Sophie Martou, Félix Jaumaux, Philippe Gabant, Jacques Mahillon, Jan‐Willem Veening, Johann Mignolet, Pascal Hols A

This paper identifies novel class II bacteriocins in Streptococcus salivarius using bioinformatics and synthetic biology, revealing 50 candidates active against Gram-positive pathogens.

Communications Biology · Nov 14, 2024Peer-reviewedMicrobiology