Author

María Mercedes Hincapié-Otero

University of HelsinkiORCID 0000-0001-8750-1729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Ada JunqueraiD· 2 shared Anna VähärautioiD· 2 shared Anni VirtaneniD· 2 shared Anniina FärkkiläiD· 2 shared Essi KaheliniD· 2 shared Fernando Pérez‐VillatoroiD· 2 shared Foteini ChamchougiaiD· 2 shared Iga NiemieciD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Ada JunqueraORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedFeb 9, 2026

✦ In-depth digest

Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes

Fernando Pérez‐Villatoro, Aleksandra Shabanova, Lilian van Wagensveld…·Anniina Färkkilä

Cyclic immunofluorescence of 265 high-grade serous ovarian carcinomas and random-forest feature ranking identify cancer-cell MHC-II as an adjusted predictor of longer survival marking immune-activated tumor-stroma hotspots.

10 citationstop 1%

humanimaging

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Cancer BiologyCancer CellPeer-reviewedDec 1, 2024

Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer

Inga-Maria P. Launonen, Iga Niemiec, María Mercedes Hincapié-Otero…·Anniina Färkkilä

This study shows chemotherapy causes myeloid-driven spatial T-cell exhaustion in ovarian cancer by altering immune cell states and interactions, suggesting new immunotherapy approaches.

103 citationstop 1%

humanscRNA-seq

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