Author

Inga-Maria P. Launonen

University of HelsinkiORCID 0000-0002-4548-9650Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Anniina FärkkiläiD· 4 shared Anni VirtaneniD· 3 shared Ada JunqueraiD· 2 shared Angela Szabo· 2 shared Anna VähärautioiD· 2 shared Daria AfentevaiD· 2 shared Erdoğan Pekcan ErkaniD· 2 shared Fernando Pérez‐VillatoroiD· 2 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Anniina FärkkiläORCID

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4 papers

Recent·Most cited

Integrative single-cell and spatial mapping of oxidative stress response uncovers GCLC+ mesenchymal tumor cell state linked with favorable outcomes in triple negative breast cancer

Nomeda Girnius, Tuulia Vallius, Wenqing Chen, Inga-Maria P. Launonen, Sara Palomino‐Echeverría, Jia‐Ren Lin, Caitlin E. Mills, Saila Kauppila, Pauliina Kronqvist, Antti Ellonen, Merja Perälä, Eloise Withnell, Yu‐An Chen, Maria Secrier, Sandro Santagata, , Anniina Färkkilä

The paper maps oxidative stress response in TNBC using single-cell and spatial data, identifying GCLC+ mesenchymal tumor cells linked to better patient outcomes.

bioRxiv · Nov 6, 2025 · PreprintCancer Biology

Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer

Daria Afenteva, Rong Yu, Anna Rajavuori, Marina Salvadores, Inga-Maria P. Launonen, Kari Lavikka, Kaiyang Zhang, Anna Pirttikoski, Giovanni Marchi, Sanaz Jamalzadeh, Veli‐Matti Isoviita, Yilin Li, Giulia Micoli, Erdoğan Pekcan Erkan, Matías Marín Falco, , Sampsa Hautaniemi

The paper identifies reduced IFN-I pathway activity as a driver of chemo-refractory ovarian cancer using multi-omics analysis in a clinical trial cohort.

Cell Reports Medicine · Aug 29, 2025Peer-reviewedCancer Biology

Tribus: Semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomicdata

Ziqi Kang, Angela Szabo, Teodora Farago, Fernando Pérez‐Villatoro, Ada Junquera, Shah Saundarya, Inga-Maria P. Launonen, Ella Anttila, Julia Casado, Kevin Meyer Elias, Anni Virtanen, Ulla‐Maija Haltia, Anniina Färkkilä

Tribus is a semi-automated tool for cell phenotyping from multiplexed imaging and proteomic data, achieving high accuracy and efficiency compared to existing methods.

Bioinformatics · Feb 19, 2025Peer-reviewedBioinformatics

Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer

Inga-Maria P. Launonen, Iga Niemiec, María Mercedes Hincapié-Otero, Erdoğan Pekcan Erkan, Ada Junquera, Daria Afenteva, Matías Marín Falco, Zhihan Liang, Matilda Salko, Foteini Chamchougia, Angela Szabo, Fernando Pérez‐Villatoro, Yilin Li, Giulia Micoli, Ashwini Sakrepatna Nagaraj, , Anniina Färkkilä

This study shows chemotherapy causes myeloid-driven spatial T-cell exhaustion in ovarian cancer by altering immune cell states and interactions, suggesting new immunotherapy approaches.

Cancer Cell · Dec 1, 2024Peer-reviewedCancer Biology