ImmunologybioRxivPreprint
RUNX2 is a cell-intrinsic brake on Th17 pathogenicity driven by neutrophil extracellular traps
Caleb Wong Han, Aaron H S Heng, Gabrielle Therese Belz…·Iain Comerford
This study shows RUNX2 suppresses Th17 pathogenicity in MS and EAE by inhibiting neutrophil extracellular trap-driven Th17 priming.
DOI 10.1101/2025.06.26.661866