Author

Sandeep Singh

Central University of PunjabORCID 0000-0001-8780-5124Unclaimed ORCID profile · follow to get notified of new preprints

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Sandeep Singh2 papers · Defence Research and Development Establishment

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anjana MunshiiD· 1 shared Prabhsimran KauriD· 1 shared Tashvinder SinghiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Anjana MunshiORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 17, 2026

Disruption of PI3K/OxPhos Coupling by Trehalose Drives a BCAA to Lipid Metabolic Switch in Hormone Receptor Positive Breast Cancer

Tashvinder Singh, Prabhsimran Kaur, Anjana Munshi, Sandeep Singh

This study shows trehalose disrupts mitochondrial-OxPhos coupling in ER+ breast cancer, inducing a metabolic switch from BCAA to lipid metabolism, and enhances the efficacy of mitochondrial-targeting therapies.

DOI 10.64898/2026.04.14.718262

humanmetabolomics