Jeffrey B. Russ

The paper introduces six novel gene knock-in mouse lines to label and study molecularly defined cortical intratelencephalic neuron subtypes with distinct projection patterns.

The paper introduces CellREADR, an RNA sensor-effector technology for targeting and manipulating specific human cortical neuron types, validated through histological, electrophysiological, and transcriptomic methods.

The paper identifies cell-specific gene expression biases in excitatory neurons and microglia for pathogenic variants linked to speech/cognitive delay and seizures using single-nucleus RNA-seq data.