Author

Jau‐Nian Chen

University of California, Los AngelesORCID 0000-0001-8807-3607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:zebrafish· 2 Organism:mouse· 1

Frequent Co-Authors

Aaron L. BrowniD· 1 shared Adam D. LangenbacheriD· 1 shared Alette Eide· 1 shared Alexander D. KaiseriD· 1 shared Alison Lesley MarsdeniD· 1 shared Atsushi NakanoiD· 1 shared Benjamin Keer· 1 shared Bin ZhouiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Aaron L. BrownORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMay 7, 2026

A Continuum of Atrial Peristalsis Initiates the Bicuspid to Quadricuspid Valve Transition

Jing Wang, Aaron L. Brown, Peng Zhao…·Tzung K. Hsiai

The paper shows that atrial peristalsis drives the transition from a bicuspid to quadricuspid valve in zebrafish through Klf2a-Snai1b signaling and shear stress alignment.

DOI 10.64898/2026.05.04.722768

zebrafishexperimental assay

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Developmental BiologyeLifePeer-reviewedJan 15, 2026

Rtf1-dependent transcriptional pausing regulates cardiogenesis

Adam D. Langenbacher, Fei Lu, Luna Tsang…·Jau‐Nian Chen

This study shows that Rtf1-mediated transcriptional pausing is essential for cardiogenesis, as its disruption leads to cardiac progenitor cell defects and cardiomyocyte absence.

4 citations

zebrafishmouse

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