Author

Kellie E. Kolb

Broad InstituteORCID 0000-0001-8840-7363Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Alex K. ShalekiD· 2 shared Benjamin E. MeadiD· 2 shared Adam J. RubiniD· 1 shared Bonnie BergeriD· 1 shared Brandon M. LehrichiD· 1 shared Brian J. Pepe-MooneyiD· 1 shared Brittany A. GoodsiD· 1 shared Carolyn L. WinstoniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Alex K. ShalekORCID

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2 papers

Recent·Most cited

Systems BiologyCellPeer-reviewedDec 22, 2025

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival

Constantine N. Tzouanas, Jessica E.S. Shay, Marc Samuel Sherman…·Alex K. Shalek

The paper shows chronic metabolic stress in liver cells drives developmental programs and functional loss, mirroring tumor states and predicting poor cancer survival.

23 citationstop 1%

mousehuman

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GenomicsProceedings of the National Academy of SciencesPeer-reviewedApr 4, 2022

Cellular and transcriptional diversity over the course of human lactation

Sarah K. Nyquist, Patricia Gao, Tessa Haining…·Brittany A. Goods

This study uses scRNA-seq to analyze human breast milk cells over lactation, identifying cell type shifts and functional changes linked to time and maternal factors.

71 citationstop 3%

humanscRNA-seq

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