Marc Samuel Sherman

This study identifies a mechanism by which macrophage-derived IL-27 sustains autoreactive CD8+ T cells in autoimmune hepatitis through a local progenitor-to-effector pipeline.

This study identifies CD8+TOX+ T-cells as a specific marker for autoimmune hepatitis using single-nucleus RNA sequencing.

This study identifies the adrenal as the primary site limiting HPA axis recovery after chronic glucocorticoid treatment in male mice, showing adrenocortical cell loss and steroidogenesis defects.

The paper shows chronic metabolic stress in liver cells drives developmental programs and functional loss, mirroring tumor states and predicting poor cancer survival.

This paper harmonizes TUNEL with multiplexed immunofluorescence to improve spatial contextualization of cell death in tissues.

This study uses single-nucleus multi-omics to analyze fibrolamellar carcinoma, revealing rewired cell communication and potential therapeutic targets.