Author

Sandra Elisabeth Fischer

Boehringer Ingelheim (Germany)ORCID 0000-0001-8859-4525Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:rat· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Amy Xin Wei ZhangiD· 1 shared Benjamin Haibe‐KainsiD· 1 shared Benjamin StrobeliD· 1 shared David William HedleyiD· 1 shared Deena M.A. GendooiD· 1 shared Dianne E. Chadwick· 1 shared Emin Ibrahimov· 1 shared Frank Gillardon· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Amy Xin Wei ZhangORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of Neuroscience MethodsPeer-reviewedDec 22, 2021

Two engineered AAV capsid variants for efficient transduction of human cortical neurons directly converted from iPSC

Sandra Elisabeth Fischer, Benjamin Strobel, Jonas Weinmann, Frank Gillardon

The paper evaluates two engineered AAV capsid variants for transducing human cortical neurons derived from iPSCs, finding that AAV2-NNPTPSR efficiently transduces both glutamatergic and GABAergic neurons, while AAV9-NVVRSSS also transduces astrocytes.

4 citations

humanrat

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BioinformaticsPLoS Computational BiologyPeer-reviewedJan 10, 2019

Whole Genomes Define Concordance of Matched Primary, Xenograft, and Organoid Models of Pancreas Cancer

Deena M.A. Gendoo, Robert Edward Denroche, Amy Xin Wei Zhang…·Benjamin Haibe‐Kains

The paper compares whole-genome data from primary pancreatic cancer, xenografts, and organoids to assess genetic concordance across different models.

55 citationstop 5%

humanwhole-genome sequencing

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