William A. Altemeier

This study investigates the role of mesenchymal-derived versican in modulating the innate immune response during influenza A virus infection, showing its critical role in immune cell migration and adhesion.

This study uses snRNA-seq to analyze bleomycin-induced lung injury in mice, identifying dynamic changes and rare cell types not well captured by scRNA-seq.

This study examines how shear stress and pressure affect pulmonary arterial endothelial cells in health and PAH, revealing divergent transcriptional responses across disease states and donor sex.

This study identifies canonical type I interferon signaling via ISGF3 as the mechanism regulating versican expression in macrophages exposed to LPS.

The paper introduces a low-cost system for high-throughput RNA isolation from tissues, combining CryoGrid for storage/sampling with PIXUL-based methods using a PK buffer to enable efficient transcript analysis.