Demi J. Rijlaarsdam

This paper introduces Full Scan enhanced Dynamic Range MS to improve metabolite detection in untargeted metabolomics, increasing feature detection and enabling better discrimination between cancer cell lines.

This study shows that hepatic stellate cells enhance HCC proliferation through HIF-dependent metabolic changes and H2O2 signaling.

The paper develops a framework to integrate metabolic gene expression and nutrient availability into genome-scale metabolic models to study osteosarcoma metabolism under different glucose and glutamine conditions.