BioinformaticsChemical SciencePeer-reviewed
Transfer learning enables discovery of sub-micromolar antibacterials for ESKAPE pathogens from ultra-large chemical spaces
Miguel García-Ortegón, Srijit Seal, Emily J. Geddes…·Sergio Bacallado
This paper uses transfer learning to identify potent antibacterials from large chemical libraries, finding 54% of tested compounds active against E. coli with sub-micromolar potency.
4 citations