Author

Collette S. Guy

University of WarwickORCID 0000-0002-5153-0613Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreas BenderiD· 1 shared Carl Edward RasmusseniD· 1 shared Emily J. GeddesiD· 1 shared Jenny L. Littler· 1 shared Jonathan WhitesideiD· 1 shared Miguel García-OrtegóniD· 1 shared Sergio BacalladoiD· 1 shared Srijit SealiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Andreas BenderORCID

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1 paper

Recent·Most cited

Transfer learning enables discovery of sub-micromolar antibacterials for ESKAPE pathogens from ultra-large chemical spaces

Miguel García-Ortegón, Srijit Seal, Emily J. Geddes, Jenny L. Littler, Collette S. Guy, Jonathan Whiteside, Carl Edward Rasmussen, Andreas Bender, Sergio Bacallado

This paper uses transfer learning to identify potent antibacterials from large chemical libraries, finding 54% of tested compounds active against E. coli with sub-micromolar potency.

Chemical Science · Jan 1, 2025Peer-reviewedBioinformatics