Martin Mikl

The paper shows isoform diversity is a distinct dimension of gene expression, complementary to gene-level abundance, and changes with age and tissue-specific processes.

The paper shows that COX-2 proteolysis generates catalytically inactive fragments that affect mitochondrial function and cell proliferation in colon tumors.

The paper uses a massively parallel reporter assay to identify RNA localization signals in neurons, revealing focused and broadly encoded motifs that influence mRNA localization to neurites and soma.

The paper develops a high-throughput method to assess ribosomal frameshifting potential and identifies factors influencing frameshifting rates in HIV and other organisms.

The paper uses a designed sequence library to study splicing regulation and cell-to-cell variability in splicing decisions.