Luis M. Colón-Pérez

This study examines sex differences in blood pressure, autonomic activity, and inflammation in rats exposed to a low resource environment during early life, finding increased BP in males and potential protective effects in females.

This paper identifies and validates non-covalent inhibitors of RGS14 GAP activity using structure-guided virtual screening and machine learning, showing improved potency and CNS penetration.

The paper identifies four subtypes of neurodevelopmental trajectories in the ABCD Study associated with impulsivity and cortical thickness changes.

This study shows that morphine self-administration in rodents alters gut microbiota and brain microstructure, with neuroinflammation linking gut and brain changes.

This study identifies macro- and micro-structural midbrain alterations in early psychosis using multimodal MRI analyses and links them to clinical outcomes.

StandardRat improves functional connectivity specificity in rat brains through a standardized MRI protocol tested across 20 centers.

The paper shows that a familiar contextual stimulus before imaging alters functional connectivity metrics like network strength and eigenvector centrality in rats, while an unfamiliar social stimulus does not.

This study uses multi-scale imaging to show that aged rats have altered functional connectivity and increased dorsal striatal Arc expression during cognitive multi-tasking.

The paper uses dMRI to study how Aβ and IL6 affect microstructure in TgCRND8 mice, finding increased neurite density and dispersion linked to reduced functional network organization.